:root{--bg: #FFFFFF;--surface: #F7F8F8;--surface-2: #F3F4F4;--soft: #F0F1F1;--line: #E6E8E9;--line-2: #CFD3D5;--ink: #0E1416;--ink-soft: #5B666C;--ink-faint: #93A0A6;--glow: rgba(14, 20, 22, .1);--max: 1080px;--font-body: "Geist", -apple-system, BlinkMacSystemFont, system-ui, sans-serif}html[data-theme=dark]{--bg: #0A0A0A;--surface: #141414;--surface-2: #161616;--soft: #1A1A1A;--line: #262626;--line-2: #3F3F46;--ink: #FAFAFA;--ink-soft: #A3A3A3;--ink-faint: #71717A;--glow: rgba(255, 255, 255, .1)}*{margin:0;padding:0;box-sizing:border-box}html{scroll-behavior:smooth}body{background:var(--bg);color:var(--ink);font-family:var(--font-body);font-size:16px;line-height:1.6;-webkit-font-smoothing:antialiased;transition:background .3s ease,color .3s ease}a{color:inherit}::selection{background:color-mix(in srgb,var(--ink) 14%,transparent)}.mono{font-family:var(--font-body);font-weight:500;font-size:.7rem;letter-spacing:.16em;text-transform:uppercase;color:var(--ink-faint)}nav{position:fixed;top:0;left:0;right:0;z-index:10;display:flex;justify-content:space-between;align-items:center;padding:1rem 2rem;backdrop-filter:blur(12px);-webkit-backdrop-filter:blur(12px);background:color-mix(in srgb,var(--bg) 75%,transparent);border-bottom:1px solid transparent;transition:border-color .3s ease,background .3s ease}nav.scrolled{border-bottom-color:var(--line)}.nav-name{display:inline-flex;align-items:center;text-decoration:none;color:var(--ink)}.nav-logo{width:1.7rem;height:1.7rem;display:block}[data-theme=dark] .nav-logo-light,[data-theme=light] .nav-logo-dark{display:none}.nav-links{display:flex;gap:1.5rem;align-items:center}.nav-links a{font-weight:500;font-size:.68rem;letter-spacing:.12em;text-transform:uppercase;text-decoration:none;color:var(--ink-soft);transition:color .2s}.nav-links a:hover,.nav-links a:focus-visible{color:var(--ink)}.theme-toggle{display:inline-flex;align-items:center;justify-content:center;width:34px;height:34px;border:1px solid var(--line-2);border-radius:999px;color:var(--ink);background:transparent;cursor:pointer;transition:border-color .2s,background .2s,box-shadow .2s}.theme-toggle:hover,.theme-toggle:focus-visible{border-color:var(--ink);background:var(--soft);box-shadow:0 0 0 4px var(--glow)}.theme-toggle svg{width:17px;height:17px;display:block}.theme-toggle .i-sun{display:none}html[data-theme=dark] .theme-toggle .i-sun{display:block}html[data-theme=dark] .theme-toggle .i-moon{display:none}section{max-width:var(--max);margin:0 auto;padding:5rem 2rem 1.5rem}.section-head{display:flex;align-items:baseline;justify-content:space-between;gap:1rem;border-bottom:1px solid var(--line);padding-bottom:1rem;margin-bottom:.5rem}.section-head h2{font-weight:600;font-size:1.9rem;letter-spacing:-.025em}.section-head a{text-decoration:none;transition:color .2s}.section-head a:hover,.section-head .mono:hover{color:var(--ink)}.article-list{list-style:none}.article-list li{border-bottom:1px solid var(--line)}.article-list a{display:grid;grid-template-columns:1fr auto;gap:.35rem 2rem;align-items:baseline;text-decoration:none;padding:1.5rem .5rem;border-radius:10px;transition:background .2s ease,padding-left .25s ease}.article-list a:hover,.article-list a:focus-visible{background:var(--soft);padding-left:1rem}.article-title{font-weight:500;font-size:1.32rem;line-height:1.32;letter-spacing:-.015em;transition:color .2s}.article-list a:hover .article-title{color:var(--ink-soft)}.article-meta{text-align:right;white-space:nowrap}.article-desc{grid-column:1 / -1;color:var(--ink-soft);font-size:.93rem;max-width:64ch}.widget-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(280px,1fr));gap:1rem;padding-top:1.5rem}.widget-card{display:block;text-decoration:none;border:1px solid var(--line);border-radius:18px;padding:1.6rem 1.5rem;background:var(--surface);transition:transform .2s ease,border-color .2s ease,box-shadow .2s ease}.widget-card:hover,.widget-card:focus-visible{transform:translateY(-4px);border-color:var(--line-2);box-shadow:0 0 0 1px var(--glow),0 16px 36px -22px var(--glow)}.widget-card .mono{color:var(--ink-soft)}.widget-card h3{font-weight:600;font-size:1.3rem;letter-spacing:-.02em;margin:.7rem 0 .5rem}.widget-card p{color:var(--ink-soft);font-size:.9rem;line-height:1.55}.widget-card .run{display:inline-flex;align-items:center;gap:6px;margin-top:1.1rem;font-weight:500;font-size:.68rem;letter-spacing:.12em;text-transform:uppercase;color:var(--ink-faint);transition:color .2s,gap .2s}.widget-card:hover .run{color:var(--ink);gap:10px}.about{display:grid;grid-template-columns:200px 1fr;gap:2.5rem;align-items:start}.about p{color:var(--ink-soft);max-width:62ch}.about p+p{margin-top:1rem}.about strong{color:var(--ink);font-weight:600}footer{margin-top:5rem;border-top:1px solid var(--line);background:var(--surface-2)}.footer-inner{max-width:var(--max);margin:0 auto;padding:2.2rem 2rem;display:flex;justify-content:space-between;align-items:center;gap:1.5rem;flex-wrap:wrap}.footer-links{display:flex;gap:1.4rem}.footer-links a{font-size:.84rem;color:var(--ink-soft);text-decoration:none;transition:color .2s}.footer-links a:hover,.footer-links a:focus-visible{color:var(--ink)}header.hero{position:relative;min-height:100svh;display:flex;align-items:center;overflow:hidden}#field{position:absolute;inset:0;width:100%;height:100%;display:block}.hero-inner{position:relative;z-index:2;width:100%;max-width:var(--max);margin:0 auto;padding:6rem 2rem 4rem}.hero-eyebrow{display:inline-flex;align-items:center;gap:.55rem;margin-bottom:2rem;font-weight:600;font-size:.82rem;letter-spacing:.16em;color:var(--ink-soft);opacity:0;animation:rise .8s ease .1s forwards}.hero-eyebrow:before{content:"";width:2rem;height:1px;background:var(--ink-soft)}h1{font-family:var(--font-body);font-weight:600;font-size:clamp(2.5rem,6vw,4.2rem);line-height:1.04;letter-spacing:-.035em;max-width:16ch;color:var(--ink);opacity:0;animation:rise .8s ease .25s forwards}.scroll-hint{position:absolute;bottom:1.4rem;left:50%;transform:translate(-50%);z-index:2;font-weight:500;font-size:.6rem;letter-spacing:.25em;color:var(--ink-faint);text-decoration:none;display:flex;flex-direction:column;align-items:center;gap:.5rem;opacity:0;animation:rise .8s ease 1s forwards}.scroll-hint:after{content:"";width:1px;height:2.2rem;background:linear-gradient(var(--ink-faint),transparent);animation:drip 2.2s ease-in-out infinite}@keyframes rise{0%{opacity:0;transform:translateY(14px)}to{opacity:1;transform:translateY(0)}}@keyframes drip{0%,to{transform:scaleY(.4);transform-origin:top;opacity:.4}50%{transform:scaleY(1);opacity:1}}.prose-wrap{max-width:720px;margin:0 auto;padding:8rem 2rem 2rem}.back-link{display:inline-block;text-decoration:none;margin-bottom:2rem;transition:color .2s}.back-link:hover{color:var(--ink-soft)}.article-tag{display:block;color:var(--ink-faint);margin-bottom:.8rem}.prose-title{font-family:var(--font-body);font-weight:600;font-size:clamp(2rem,4.5vw,2.9rem);line-height:1.1;letter-spacing:-.03em;margin-bottom:1.2rem;opacity:1;animation:none;max-width:none}.prose-lead{font-size:1.22rem;line-height:1.55;color:var(--ink-soft);margin-bottom:2.4rem;padding-bottom:2.4rem;border-bottom:1px solid var(--line)}.prose{font-size:1.12rem;line-height:1.75;color:var(--ink)}.prose>*+*{margin-top:1.3rem}.prose h2{font-weight:600;font-size:1.5rem;letter-spacing:-.02em;margin-top:2.6rem}.prose h3{font-weight:600;font-size:1.2rem;letter-spacing:-.015em;margin-top:2rem}.prose a{color:var(--ink);text-underline-offset:3px;text-decoration-color:var(--line-2)}.prose a:hover{text-decoration-color:var(--ink)}.prose strong{font-weight:600}.prose blockquote{border-left:2px solid var(--line-2);padding-left:1.3rem;color:var(--ink-soft);font-style:italic}.prose code{font-family:ui-monospace,SFMono-Regular,Menlo,monospace;font-size:.85em;background:var(--surface);border:1px solid var(--line);padding:.1em .35em;border-radius:5px}.prose ul,.prose ol{padding-left:1.4rem}.prose li+li{margin-top:.4rem}.tool-lead{color:var(--ink-soft);font-size:1rem;padding:1rem 0 1.5rem}.tool{display:grid;gap:1.5rem;border:1px solid var(--line);border-radius:18px;padding:1.6rem 1.5rem;background:var(--surface);margin:1.5rem 0}.tool-controls{display:grid;grid-template-columns:repeat(auto-fit,minmax(120px,1fr));gap:1rem}.tool-field{display:flex;flex-direction:column;gap:.35rem}.tool-field>span{font-weight:500;font-size:.66rem;letter-spacing:.12em;text-transform:uppercase;color:var(--ink-faint)}.tool-field--wide{width:100%}.tool-field em{font-style:normal;font-size:.78rem;color:var(--ink-faint)}.tool-note{margin:0;font-size:.78rem;line-height:1.5;color:var(--ink-faint)}.tool input,.tool select{font:inherit;font-size:.95rem;color:var(--ink);background:var(--bg);border:1px solid var(--line-2);border-radius:8px;padding:.5rem .6rem;transition:border-color .2s,box-shadow .2s}.tool input:focus,.tool select:focus{outline:none;border-color:var(--ink);box-shadow:0 0 0 4px var(--glow)}.tool-chart{width:100%;height:auto;display:block}.tool-chart-label{font-size:13px;font-weight:600;fill:var(--ink)}.tool-chart-tick{font-size:11px;fill:var(--ink-faint)}.jfig-wrap{margin:1.6rem 0 1.8rem}.jfig{border:1px solid var(--line);border-radius:12px;background:var(--surface);padding:.6rem .4rem .2rem}.jfig-axis{font-size:12px;fill:var(--ink-soft)}.jfig-annot{font-size:11px;font-weight:600;fill:var(--ink);paint-order:stroke;stroke:var(--surface);stroke-width:3px;stroke-linejoin:round}.jfig-reflabel{font-size:11px;fill:var(--ink-faint)}.jfig-legend{display:flex;flex-wrap:wrap;gap:.4rem 1.1rem;justify-content:center;margin-top:.55rem}.jfig-legend-item{display:inline-flex;align-items:center;gap:.4rem;font-size:.82rem;color:var(--ink-soft)}.jfig-cap{font-size:.86rem;line-height:1.55;color:var(--ink-soft);margin:.7rem .2rem 0}.jfig-cap strong{color:var(--ink)}.prose details.eq-explanation{margin:1rem 0 1.4rem;border:1px solid var(--line);border-radius:10px;background:var(--surface);padding:0 1.05rem}.prose details.eq-explanation>summary{cursor:pointer;font-weight:600;font-size:.9rem;color:var(--ink);padding:.7rem 0;list-style:none}.prose details.eq-explanation>summary::-webkit-details-marker{display:none}.prose details.eq-explanation>summary:before{content:"＋ ";color:var(--ink-faint);font-weight:400}.prose details.eq-explanation[open]>summary:before{content:"－ "}.prose details.eq-explanation[open]>summary{border-bottom:1px solid var(--line);margin-bottom:.7rem}.eq-explanation-content{font-size:.9rem;color:var(--ink-soft);padding-bottom:.7rem}.eq-explanation-content strong{color:var(--ink)}.eq-explanation-content table{font-size:.85rem}.prose figure,.prose details img{margin:0}.prose img{max-width:100%;height:auto;border-radius:8px;display:block}.prose details>summary{cursor:pointer}.prose .orig{position:relative;font-family:Iowan Old Style,Palatino Linotype,Palatino,Georgia,Times New Roman,serif;font-size:1.02rem;line-height:1.72;background:var(--surface);border:1px solid var(--line);border-radius:12px;padding:1.6rem 1.6rem 1.2rem;margin:1.7rem 0 .5rem;color:var(--ink)}.prose .orig:before{content:"Originaltext · Jacobsson 1983";position:absolute;top:0;left:1.3rem;transform:translateY(-50%);background:var(--bg);padding:.15rem .6rem;font-family:var(--font-body);font-weight:500;font-size:.62rem;letter-spacing:.14em;text-transform:uppercase;color:var(--ink-faint);border:1px solid var(--line);border-radius:999px}.prose .orig>:first-child{margin-top:0}.prose .orig>:last-child{margin-bottom:0}.prose .orig :is(h2,h3){font-family:inherit;font-weight:700;letter-spacing:-.01em;margin:0 0 1rem;padding-bottom:.55rem;border-bottom:1px solid var(--line)}.prose .orig h2{font-size:1.38rem}.prose .orig h3{font-size:1.12rem}.prose .forklaring{margin:.9rem 0 2rem}.prose .forklaring:before{content:"Kommentar";display:block;font-family:var(--font-body);font-weight:500;font-size:.62rem;letter-spacing:.16em;text-transform:uppercase;color:var(--ink-faint);margin-bottom:.55rem}.prose .forklaring.harledning:before{content:"Härledning"}.prose .forklaring>:last-child{margin-bottom:0}.prose .forklaring strong{color:var(--ink)}.prose .katex-display{margin:1.15rem 0;padding:.2rem .1rem;overflow-x:auto;overflow-y:hidden}.prose .orig p{margin:1rem 0}.prose .orig .katex-display{margin:1.45rem 0}.prose .forklaring .katex-display{margin:1rem 0}.prose .callout-note{border-left:3px solid var(--ink-faint);background:var(--surface);border-radius:0 10px 10px 0;padding:.9rem 1.1rem;margin:1.4rem 0;font-size:.92rem}.prose .callout-note>:first-child{margin-top:0}.prose .callout-note>:last-child{margin-bottom:0}.tool-verdict{margin:0;padding:.9rem 1.1rem;border-radius:12px;border:1px solid var(--line-2);background:var(--soft);font-size:.95rem;color:var(--ink-soft)}.tool-verdict strong{color:var(--ink)}.tool-verdict[data-state=signal]{border-color:var(--ink)}.io{gap:1.25rem}.io-results{display:grid;grid-template-columns:repeat(auto-fit,minmax(140px,1fr));gap:.75rem}.io-result{border:1px solid var(--line);border-radius:14px;background:var(--bg);padding:.9rem 1rem;display:flex;flex-direction:column;gap:.15rem}.io-result-label{font-size:.64rem;letter-spacing:.12em;text-transform:uppercase;color:var(--ink-faint);font-weight:500}.io-result-value{font-size:1.85rem;font-weight:600;letter-spacing:-.02em;line-height:1.1}.io-result-unit{font-size:.78rem;color:var(--ink-soft)}.io-page{display:grid;grid-template-columns:1fr 1fr;gap:1rem;align-items:start}.io-form{display:grid;gap:1rem;align-content:start}.io-headline{border:1px solid var(--line-2);border-radius:14px;background:var(--bg);padding:.9rem 1.1rem;display:flex;flex-direction:column;gap:.1rem}.io-headline-value{font-size:2.5rem;font-weight:600;letter-spacing:-.03em;line-height:1}.io-stats{display:grid;grid-template-columns:repeat(2,1fr);gap:.6rem;align-content:start}.io-stat{border:1px solid var(--line);border-radius:12px;background:var(--surface);padding:.7rem .85rem;display:flex;flex-direction:column;gap:.1rem}.io-stat-label{font-size:.6rem;letter-spacing:.1em;text-transform:uppercase;color:var(--ink-faint);font-weight:500}.io-stat-value{font-size:1.35rem;font-weight:600;letter-spacing:-.02em;line-height:1.15}.io-stat-unit{font-size:.7rem;color:var(--ink-soft)}@media (max-width: 720px){.io-page{grid-template-columns:1fr}}.field-grid{display:grid;grid-template-columns:repeat(2,1fr);gap:.7rem}.ff{position:relative;min-width:0;border:1px solid var(--line-2);border-radius:10px;background:var(--bg);transition:border-color .2s,box-shadow .2s}.ff:focus-within{border-color:var(--ink);box-shadow:0 0 0 4px var(--glow)}.io .ff-input{width:100%;border:none;background:transparent;font:inherit;font-size:.95rem;color:var(--ink);padding:1.45rem .75rem .4rem;outline:none;border-radius:10px}.io .ff-input:focus,.io .ff-input:focus-visible{border:none;box-shadow:none}.io .ff--unit .ff-input{padding-right:2.8rem}.ff-label{position:absolute;left:.78rem;top:.42rem;color:var(--ink-faint);font-size:.6rem;letter-spacing:.08em;text-transform:uppercase;pointer-events:none;transition:color .15s ease}.ff:focus-within .ff-label{color:var(--ink)}.ff-unit{position:absolute;right:.75rem;top:1.5rem;color:var(--ink-faint);font-size:.85rem;pointer-events:none;white-space:nowrap}.io .ff-input[type=number]::-webkit-outer-spin-button,.io .ff-input[type=number]::-webkit-inner-spin-button{-webkit-appearance:none;margin:0}.io .ff-input[type=number]{-moz-appearance:textfield;appearance:textfield}.sheet{display:grid;gap:.4rem}.sheet-label{display:flex;align-items:center;justify-content:space-between;gap:1rem;font-weight:500;font-size:.66rem;letter-spacing:.12em;text-transform:uppercase;color:var(--ink-faint)}.sheet-count{display:inline-flex;align-items:center;gap:.4rem}.sheet-count select{font:inherit;font-size:.66rem;letter-spacing:.04em;color:var(--ink);background:var(--bg);border:1px solid var(--line-2);border-radius:6px;padding:.15rem .3rem}.sheet-scroll{overflow-x:auto;border-radius:10px}.sheet-grid{display:grid;gap:1px;background:var(--line);border:1px solid var(--line);border-radius:10px;overflow:hidden;font-size:.85rem}.sheet-head{background:var(--surface-2);color:var(--ink-faint);font-size:.62rem;letter-spacing:.06em;text-transform:uppercase;font-weight:500;padding:.45rem .6rem;display:flex;align-items:center;white-space:nowrap}.sheet-cell{background:var(--bg);display:flex;align-items:center}.sheet-cell>input,.sheet-cell>select{width:100%;border:none;background:transparent;font:inherit;color:var(--ink);padding:.5rem .6rem;outline:none;border-radius:0}.sheet-cell:focus-within{background:var(--soft);box-shadow:inset 0 0 0 2px var(--ink)}.io-setting .sheet-cell,.op-setting .sheet-cell{border-bottom-left-radius:9px;border-bottom-right-radius:9px}.sheet-cell-n{justify-content:center;color:var(--ink-faint);font-variant-numeric:tabular-nums}details.io-section{border-top:1px solid var(--line);padding-top:.25rem}details.io-section>summary{cursor:pointer;list-style:none;font-weight:500;font-size:.7rem;letter-spacing:.12em;text-transform:uppercase;color:var(--ink-faint);padding:.5rem 0;display:flex;align-items:center;gap:.5rem}details.io-section>summary::-webkit-details-marker{display:none}details.io-section>summary:before{content:"▸";transition:transform .2s ease}details.io-section[open]>summary:before{transform:rotate(90deg)}details.io-section[open]>summary{color:var(--ink)}details.io-section>.tool-controls,details.io-section>.tool-chart{margin-top:.5rem}.io-reference{margin-top:1.5rem;display:grid;gap:.25rem}.io-refs{padding:.5rem 0 .75rem;display:grid;gap:1.4rem}.ref-group h3{font-size:.66rem;letter-spacing:.12em;text-transform:uppercase;font-weight:600;color:var(--ink-soft);margin:0 0 .6rem}.ref-list{margin:0;padding:0;list-style:none;display:grid;gap:.6rem;font-size:.82rem;line-height:1.5;color:var(--ink-soft)}.ref-list li{display:grid;grid-template-columns:2.2rem 1fr;gap:.4rem;scroll-margin-top:5rem}.ref-list li:target{background:var(--soft);border-radius:6px}.ref-num{font-variant-numeric:tabular-nums;color:var(--ink-faint);font-weight:600}.ref-text{min-width:0}.ref-link{white-space:nowrap;font-size:.72rem;font-variant-numeric:tabular-nums;color:var(--ink-faint);text-decoration:none;border-bottom:1px solid var(--line-2)}.ref-link:hover{color:var(--ink);border-color:var(--ink)}.io-method{padding:.4rem 0 .5rem;display:grid;gap:.3rem}details.io-subsection{border-top:1px solid var(--line)}details.io-subsection>summary{cursor:pointer;list-style:none;font-size:.8rem;font-weight:500;color:var(--ink-soft);padding:.55rem 0;display:flex;align-items:center;gap:.5rem}details.io-subsection>summary::-webkit-details-marker{display:none}details.io-subsection>summary:before{content:"+";font-size:.95rem;width:.9rem;color:var(--ink-faint);transition:transform .2s ease}details.io-subsection[open]>summary:before{content:"−";color:var(--ink)}details.io-subsection[open]>summary{color:var(--ink)}.method-card{border-left:2px solid var(--line);padding:.2rem 0 .8rem 1rem;margin-bottom:.4rem;font-size:.85rem;color:var(--ink-soft);line-height:1.55}.method-card h4{font-size:.82rem;font-weight:600;color:var(--ink);margin:0 0 .5rem}.method-card p{margin:0 0 .5rem}.method-card em{font-style:italic}.method-note{font-size:.78rem;color:var(--ink-faint);border-top:1px dashed var(--line);padding-top:.5rem}.math-block{display:grid;gap:.55rem;margin:.4rem 0 .7rem}.math-block .katex-display{margin:0;text-align:left;overflow-x:auto;overflow-y:hidden}.math-block .katex-display>.katex{text-align:left}.math-block .katex{font-size:1em;color:var(--ink)}.formula-row{display:flex;align-items:baseline;gap:.6rem}.formula-math{flex:1;min-width:0}.formula-math .katex-display{margin:0}.formula-ref,.method-card h4 .formula-ref{flex:none;font-size:.72rem;font-variant-numeric:tabular-nums;font-weight:600;color:var(--ink-faint);white-space:nowrap}.formula-ref a{color:inherit;text-decoration:none}.formula-ref a:hover{color:var(--ink)}.method-card h4 .formula-ref{margin-left:.4rem}@media (max-width: 640px){.io-results{position:sticky;top:3.2rem;z-index:3;background:var(--surface);padding:.5rem 0;margin:-.5rem 0}}.io-reset-btn{justify-self:start;font:inherit;font-size:.72rem;font-weight:500;letter-spacing:.06em;text-transform:uppercase;color:var(--ink-soft);background:var(--surface-2);border:1px solid var(--line);border-radius:8px;padding:.45rem .9rem;cursor:pointer;transition:color .2s,border-color .2s,background .2s}.io-reset-btn:hover{color:var(--ink);border-color:var(--ink-faint);background:var(--soft)}.egfr-modes{display:inline-flex;gap:2px;padding:2px;background:var(--surface-2);border:1px solid var(--line);border-radius:10px;margin-bottom:1rem}.egfr-mode{font:inherit;font-size:.8rem;font-weight:500;letter-spacing:.02em;color:var(--ink-soft);background:transparent;border:none;border-radius:8px;padding:.4rem 1.1rem;cursor:pointer;transition:background .15s,color .15s}.egfr-mode[data-on=true]{background:var(--bg);color:var(--ink);box-shadow:0 1px 2px #0000000f}.egfr-cards{display:flex;flex-wrap:wrap;align-items:stretch;gap:.75rem;margin-bottom:1.4rem}.egfr-card{display:flex;flex-direction:column;justify-content:space-between;gap:.35rem;border:1px solid var(--line);border-radius:12px;padding:.7rem .9rem;background:var(--bg);min-width:0}.egfr-card-label{font-size:.62rem;letter-spacing:.1em;text-transform:uppercase;font-weight:500;color:var(--ink-faint)}.egfr-card--mean{min-width:9rem}.egfr-card-value{font-size:1.8rem;font-weight:600;letter-spacing:-.02em;line-height:1;color:var(--ink)}.egfr-card-unit{font-size:.7rem;color:var(--ink-faint)}.egfr-card--stage{min-width:9rem}.egfr-stage{font-size:1.8rem;font-weight:700;line-height:1;color:var(--ink)}.egfr-stage-desc{font-size:.7rem;color:var(--ink-faint)}.egfr-card--stage[data-stage=G1] .egfr-stage{color:#1a7f37}.egfr-card--stage[data-stage=G2] .egfr-stage{color:#4a8a1f}.egfr-card--stage[data-stage=G3a] .egfr-stage{color:#9a6a00}.egfr-card--stage[data-stage=G3b] .egfr-stage{color:#b5560a}.egfr-card--stage[data-stage=G4] .egfr-stage{color:#c2400a}.egfr-card--stage[data-stage=G5] .egfr-stage{color:#b3261e}.egfr-card--wide{flex:1 1 320px}.egfr-chips{display:flex;flex-wrap:wrap;gap:.4rem;align-content:flex-start}.egfr-chip{display:flex;align-items:baseline;gap:.35rem;background:var(--bg);border:1px solid var(--line);border-radius:7px;padding:.2rem .5rem}.egfr-chip-name{font-size:.72rem;color:var(--ink-soft)}.egfr-chip-val{font-size:.82rem;font-weight:600;color:var(--ink)}.egfr-chip[data-empty=true] .egfr-chip-val{color:var(--ink-faint)}.egfr-cols{display:grid;grid-template-columns:minmax(190px,.75fr) 1fr 1fr;gap:1.5rem;align-items:start}@media (max-width: 820px){.egfr-cols{grid-template-columns:1fr}}.egfr-patient{display:grid;gap:.6rem}.egfr-fields{display:grid;gap:.55rem;padding:.6rem}.egfr-group{display:grid;gap:.4rem}.egfr-rows{display:grid;gap:.3rem}.op-grid{display:grid;grid-template-columns:minmax(220px,1fr) 1fr;gap:1.5rem;align-items:start}@media (max-width: 640px){.op-grid{grid-template-columns:1fr}}.op-setting{margin-top:.6rem}.kidcalc-fields{display:grid;grid-template-columns:1fr 1fr;gap:.55rem;padding:.6rem}@media (max-width: 480px){.kidcalc-fields{grid-template-columns:1fr}}.kidcalc-formula{font-style:italic;color:var(--ink)}.testo-top{display:flex;flex-wrap:wrap;gap:1rem;margin-bottom:1.25rem}.testo-top .io-headline{flex:1 1 14rem}.testo-cols{display:grid;grid-template-columns:minmax(240px,.85fr) 1.15fr;gap:1.5rem;align-items:start}@media (max-width: 820px){.testo-cols{grid-template-columns:1fr}}.testo-input{display:grid;gap:.6rem}.testo-adv-toggle{justify-self:start;font:inherit;font-size:.8rem;color:var(--ink-soft);background:none;border:none;cursor:pointer;padding:.15rem .1rem}.testo-adv-toggle:hover{color:var(--ink)}.testo-adv-note{margin:.4rem .6rem .2rem}.testo-results{display:grid;gap:.4rem}.testo-table{width:100%;border-collapse:collapse;font-size:.85rem}.testo-table th{text-align:left;font-weight:500;font-size:.68rem;letter-spacing:.04em;text-transform:uppercase;color:var(--ink-faint);padding:.3rem .6rem;border-bottom:1px solid var(--line-2)}.testo-table th:not(:first-child),.testo-table td:not(:first-child){text-align:right}.testo-group td{font-size:.68rem;letter-spacing:.04em;text-transform:uppercase;color:var(--ink-soft);font-weight:600;padding:.7rem .6rem .25rem}.testo-row td{padding:.75rem .6rem;border-bottom:1px solid var(--line);vertical-align:top}.testo-name{color:var(--ink);font-weight:500}.testo-val{font-weight:600;color:var(--ink);white-space:nowrap}.testo-val em{font-style:normal;font-size:.66rem;color:var(--ink-faint);font-weight:400;margin-left:.2rem}.testo-pct{display:block;font-size:.66rem;color:var(--ink-faint);font-weight:400}.testo-na{color:var(--ink-faint)}.testo-empty{padding:1rem .6rem;color:var(--ink-faint);text-align:center}.testo-const{border-collapse:collapse;font-size:.82rem;margin:.5rem 0}.testo-const th,.testo-const td{padding:.25rem .9rem .25rem 0;text-align:left}.testo-const th{font-weight:500;color:var(--ink-soft);border-bottom:1px solid var(--line)}.testo-const td{color:var(--ink)}.gfrk-top{display:flex;flex-wrap:wrap;align-items:stretch;gap:.8rem}.gfrk .egfr-modes{margin-bottom:0}.gfrk-top .io-headline{flex:1 1 14rem}.gfrk-top .io-stat{flex:0 1 11rem;justify-content:center}.egfr-row{display:grid;grid-template-columns:1fr auto;align-items:center;gap:.5rem;width:100%;text-align:left;font:inherit;background:var(--bg);border:1px solid var(--line);border-radius:8px;padding:.5rem .7rem;cursor:pointer;transition:background .15s,border-color .15s}.egfr-row:hover{background:var(--soft)}.egfr-row[data-on=true]{border-color:var(--ink);background:var(--soft)}.egfr-row{user-select:none}.egfr-row-name{display:flex;flex-direction:column;align-items:flex-start;font-size:.85rem;color:var(--ink)}.egfr-q-toggle{display:inline-flex;align-items:center;gap:.3rem;margin-top:.2rem;font-size:.68rem;color:var(--ink-faint);cursor:pointer}.egfr-q-toggle input{accent-color:var(--ink);cursor:pointer;width:.82rem;height:.82rem;margin:0}.egfr-q-toggle:hover{color:var(--ink-soft)}.egfr-row-val{font-size:1rem;font-weight:600;letter-spacing:-.01em;color:var(--ink);white-space:nowrap}.egfr-row-val em{font-style:normal;font-size:.66rem;color:var(--ink-faint);font-weight:400;margin-left:.3rem}.egfr-row[data-empty=true] .egfr-row-val{color:var(--ink-faint)}.egfr-footnote{margin-top:.3rem}.io-point{cursor:pointer}.io-point .io-point-marker{transition:r .12s ease}.io-point:hover .io-point-marker{r:7}.io-point-label{font-size:11px;font-weight:600;letter-spacing:.02em;fill:var(--ink-faint);pointer-events:none}.io-point-label[data-on=true]{fill:var(--ink)}.io-check{display:inline-flex;align-items:center;gap:.5rem;justify-self:start;width:fit-content;cursor:pointer;font-size:.8rem;color:var(--ink-soft);user-select:none}.io-check input{accent-color:var(--ink);cursor:pointer}.io-settings{display:grid;gap:.9rem}.subcalc-group{display:grid;gap:.4rem;margin-top:.8rem}.subcalc-settings{margin-top:1.8rem;max-width:calc(50% - .5rem)}@media (max-width: 720px){.subcalc-settings{max-width:none}}.subcalc-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(125px,1fr));gap:.5rem}.subcalc-item{display:flex;flex-direction:column;gap:.1rem;border:1px solid var(--line);border-radius:10px;background:var(--surface);padding:.55rem .7rem}.subcalc-item-label{font-size:.6rem;letter-spacing:.08em;text-transform:uppercase;color:var(--ink-faint);font-weight:500}.subcalc-item-gfr{font-size:1.05rem;font-weight:600;letter-spacing:-.01em}.subcalc-item-rel{font-size:.8rem;color:var(--ink-soft)}.subcalc-item-gfr em,.subcalc-item-rel em{font-style:normal;font-size:.7rem;color:var(--ink-soft);font-weight:400;margin-left:.2rem}:focus-visible{outline:2px solid var(--ink);outline-offset:3px;border-radius:2px}input:focus,input:focus-visible,select:focus,select:focus-visible,textarea:focus,textarea:focus-visible{outline:none}@media (prefers-reduced-motion: reduce){html{scroll-behavior:auto}*,*:before,*:after{animation-duration:.01ms!important;animation-iteration-count:1!important;transition-duration:.01ms!important}.hero-eyebrow,h1,.scroll-hint{opacity:1!important}}@media (max-width: 640px){nav{padding:.9rem 1.2rem}.nav-links{gap:1.1rem}.nav-links a{font-size:.66rem}.article-list a{grid-template-columns:1fr}.article-meta{text-align:left}.about{grid-template-columns:1fr;gap:1rem}}